【very informal 】extremely drunk.
It's manifest that he was completely loaded at that time.
关于“loaded”,之前提过一个表达：a loaded question/word （问题或词语）哄骗性的，意味深长的，另有所指的【A loaded question or word has more meaning or purpose than it appears to have, because the person who uses it hopes it will cause people to respond in a particular way.】
Mary asked if I have a thing for Mike, I guess it was a loaded question , so I didn't answer her.
2.three sheets to the wind
If you are three sheets to the wind, you have had way too much alcohol to drink.
Grandpa's three sheets to the wind and won't stop.
在过去,船上都有三条绳索,主索main sheet(控制主帆mainsail),上风帆素(windward sheet)和下风帆素(leeward sheet)。因此当一条船上三条控制船帆的绳索都飘在风中时,船便失去控制,在海面上摇摆，进而用来形容人喝得大醉,站立不稳。
If you say that someone is legless, you mean that they are extremely drunk.
They found the locals getting legless on tequila.
4.On the fritz
If you are on the fritz, you have had way too much alcohol to drink.
She drank till she was totally on the fritz.
这个短语除了能表达“喝醉”的意思外，还可以表示“出故障”【Not working correctly; acting strangely; malfunctioning.】
The telephone is on the fritz.
Someone who is fuddled cannot think clearly, for example because they are very tired or slightly drunk.
Fuddled by brandy, her brain fumbled over the events of the night.
If you are bumped, you are drunk becuse of drinking too much alcohol.
It's barmy to drink so much alcohol at the ball for you were totally bumped at that night.
Someone who is inebriated has drunk too much alcohol.
Scott was obviously inebriated by the time the dessert was served.
[not usually before noun] (old-fashioned, informal) drunk.